What is VIBERZI?

Doctor Patient Discussion

VIBERZI is a prescription medicine that helps you proactively manage IBS-D abdominal pain and diarrhea.

Taken every day, as prescribed by your healthcare provider, VIBERZI may provide continued symptom relief. VIBERZI has been shown to reduce abdominal pain and to make stools less loose and watery. VIBERZI helped patients improve their abdominal pain and diarrhea associated with Irritable Bowel Syndrome with Diarrhea (IBS-D).

VIBERZI has been shown to relieve the 2 main symptoms of IBS-D at the same time:

  • REDUCES Abdominal Pain
  • REDUCES Diarrhea

VIBERZI works in your intestine

VIBERZI is the first and only prescription therapy in a different class of medicine for IBS-D. VIBERZI acts directly in the intestine to treat abdominal pain and diarrhea.*

*This was seen in animal studies and the relevance to humans is not known.

Intestine Sensitivity Icon

VIBERZI is thought to work in TWO ways:


REDUCES nerve sensitivity in the intestine and SLOWS the movement of food through the colon

The most common side effects (>5%) of VIBERZI include:

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Constipation

Nausea Icon

Nausea

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Abdominal Pain

Stop taking VIBERZI right away and immediately call your doctor if you have constipation that is severe. These are not all the possible side effects of VIBERZI. Call your doctor for medical advice about the side effects.

Digestive System Spasm Side Effect

VIBERZI can cause serious side effects, including:

A spasm in a muscle of the digestive system (called the sphincter of Oddi), which may cause new or worsening abdominal pain. Your risk of having a spasm is increased if you do not have a gallbladder. This spasm usually happens within the first week of treatment and usually goes away when treatment is stopped.

Stop taking VIBERZI and call your doctor if you have new or worsening stomach area (abdomen) pain or pain in the upper right side of your stomach area (abdomen) that may move to your back or shoulder, with or without nausea and vomiting.

See additional Important Risk Information below and accompanying Patient Medication Guide.

Daily Dosing

Make VIBERZI part of your everyday routine

VIBERZI is 1 tablet, taken 2 times each day with food. If your healthcare provider prescribes VIBERZI, get in the habit of taking 1 tablet in the morning and 1 tablet in the evening. Taking VIBERZI every day may help you proactively manage your symptoms of IBS-D.

1 tablet in the morning WITH FOOD

Morning Icon
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Evening Icon

1 tablet in the evening WITH FOOD

Stay with it

It’s important to take VIBERZI every day as your healthcare provider prescribes. Take VIBERZI as long as your doctor recommends to continue the benefits of treatment.

Keep in mind that IBS-D symptoms may return if you stop taking VIBERZI as prescribed by your healthcare provider.

Tips for taking VIBERZI

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Take VIBERZI twice a day with food.

Make VIBERZI part of your daily routine by taking it with a morning meal and then a meal at night.

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Stay with VIBERZI for as long as your doctor prescribes.

Keep track of your supply of VIBERZI and call your healthcare provider to have your prescription refilled before you run out. Mark your calendar if you think you might forget.

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Limit use of alcohol when taking VIBERZI.

Do not take VIBERZI if you drink more than 3 alcoholic drinks a day.